Portfolio

New Portfolio since 2020

Avilar Therapeutics, Inc (MA, USA)

Extracellular protein degradation

Casma Therapeutics, Inc (MA, USA)

Targeted degradation by autophagy

Carbon Biosciences (MA, USA)

Non-AAV, Parvovirus-based vector platform

Catamaran Bio, Inc (MA, USA)

Synthetic innate immunology

DEM BioPharma, Inc (MA, USA)

Inter-cellular CRISPR screening

Mogrify Limited (Cambridge, UK)

Ex vivo/In vivo cell conversion

NeoPhore Limited (Cambridge, UK)

DNA mismatch repair system

Orna Therapeutics Holdings, LLC (MA, USA)

Circular RNA-based cell engineering

Pallando Therapeutics Inc. (CA, USA)

Tissue-sparing protein degraders

PhoreMost Limited (Cambridge, UK)

PROTAC& Peptide-based phenotypic screening

Shinobi Therapeutics Inc. (CA, USA)

Hypoimmune iPSC derived T cell therapy

Solu Therapeutics, Inc (MA, USA)

Antibody-intractable cell surface targets

Somite Therapeutics Inc. (MA, USA)

AI driven cell therapy

Stealth mode Company (Invested in 2022 Feb) (NA)

RNA biology

Syntax Bio, Inc 
(IL, USA)

Cell differentiation discovery platform

Toregem BioPharma Co., Ltd (Kyoto, Japan)

Antibody-based tooth regeneration

Turn Biotechnologies, Inc (CA, USA)

mRNA/LNP based in vivo cell rejuvenation


Former Investments

Redona Therapeutics, Inc (MA, USA)

Bicycle Therapeutics Ltd (Cambridge, UK)

IPO

Cleave Biosciences, Inc (CA, USA)

CODA Biotherapeutics, Inc (CA, USA)

Crescendo Biologics Ltd (Cambridge, UK)

eFFECTOR Therapeutics, Inc (CA, USA)

SPAC merger

Heartseed Inc (Tokyo, Japan)

IPO

Oncorus, Inc 
(MA, USA)

IPO

Tizona Therapeutics, Inc (CA, USA)

Trieza Therapeutics, Inc (MA, USA)

Trishula Terapeutics, Inc (CA, USA)

TScan Therapeutics, Inc (MA, USA)

IPO

Viamet Pharmaceuticals, Inc (NC, USA)

F2G Ltd (Manchester,UK)

PanOptica, Inc (NJ, USA)

Contact

Astellas Venture Management LLC